Scientist - Bioprocess Development

Therapeutic Area Account Manager, Hematology

Data Science Senior Manager, Measurement

The Laboratory Medicine Quality and Safety lead

Environment, Health & Safety Coordinator

Responsibilities: <ul><li>Design and set up a bioreactor lab, including coordinating with vendors to qualify and procure bioreactors and supporting equipment</li><li>Perform experimental screening of bioprocess approaches at bench-scale to establish optimal processes and operating modes in line with future commercialization targets</li><li>Develop robust, iterative scale-down processes to maximize yield and process efficiency at benchtop (&lt;10L) scale</li><li>Define key process parameters for scale-up and develop analytical methods for continuous process monitoring and control</li><li>Collaborate with other teams and members of the bioprocess group on the development and implementation of robust and scalable bioprocesses for pilot production and technology transfer for GMP manufacturing</li><li>Align with senior leadership to implement critical decisions</li><li>Lead co-development partnerships to drive shared process development goals</li><li>Conduct rigorous experimental design, documentation, and data analysis&nbsp;</li><li>Provide concise and effective reporting on project deliverables and presentation of data</li><li>Evaluate processes and assumptions for potential improvements to efficiency and manufacturability, providing creative solutions to challenging technical problems</li></ul> Requirements: <ul><li>M.S. or PhD in a relevant field (Bioengineering, Chemical Engineering, Cell Biology, or equivalent</li><li>5+ years of industry experience (MS) or 3+ years of industry experience (PhD) in biotechnology, cell manufacturing or a relevant engineering field</li><li>2+ years of direct experience in lab to mid-scale (50-500L) animal cell culture in a process development environment</li><li>Experience with batch and fed-batch cell culture is essential; intensified or continuous process experience is a plus</li><li>Tech transfer experience is preferred</li><li>Experience with scale-down model development, predictive modeling, and model validation is a plus</li><li>Experience with high throughput bioreactor systems and automation is a plus</li><li>Track record of successfully leading small teams is strongly preferred</li><li>Strong track record of peer-reviewed publications is preferred</li><li>Demonstrated scientific rigor toward continuous improvement</li><li>Proficiency with Design of Experiments (DOE) methodology for bioprocess development, including experiment design and data analysis</li><li>Proficiency in engineering techniques, including quantitative modeling and mass balance</li><li>Basic scripting in relevant languages such as Python, R, SQL, etc.</li><li>Familiarity with mammalian metabolic pathways and proficiency in metabolic flux analysis is a plus</li><li>Understanding of a range of analytical chemistry techniques necessary to support process development</li><li>Ability to work in a fast-paced, dynamic environment and skills to prioritize and deliver against timelines</li><li>Strong troubleshooting and problem-solving skills</li><li>Excellent written and verbal communication skills, including strong command of the English language</li></ul>

Overview: <ul><li>The Therapeutic Area Manager (TAM) is integral to successfully delivering this vision, working closely with healthcare providers.&nbsp;</li><li>The TAM deeply understands the specific needs of healthcare practitioners in their therapeutic area to identify and address their clinical and business goals and challenges in support of improved patient outcomes, lower costs and improved quality of care.&nbsp;</li><li>The TAM is empowered to own the business for their TA within the ecosystem and to optimize as appropriate; focused on improving the customer and patient experience across the care continuum.</li><li>They will leverage other ecosystem and organization experts to provide customers with the information they need about products to make decisions that support enhanced patient outcomes, and to influence the ecosystem business strategy. The TAM will represent all relevant products and indications within the designated Therapeutic Area.&nbsp;</li><li>In alignment with the ecosystem and customer strategic plan, the TAM is accountable for driving on-label clinical demand to ensure HCPs identify the right medication for the right patient.</li><li>In addition, they are responsible for collecting ecosystem insights and trends and being a primary conduit between an ecosystem, the Squads and marketing to support the national strategy at a local level.&nbsp;</li></ul> Responsibilities: <ul><li>Serve as primary point of contact for their therapeutic area for their customers in the ecosystem. </li><li>Address and identify opportunities for pulling through ecosystem and TA squad strategies at the point-of-care</li><li>Apply strong understanding of the specific needs of healthcare practitioners and mobilizes ecosystem and organization experts to partner with customers to identify and address their clinical and business goals and challenges in support of improved patient outcomes, lower costs and improved quality of care&nbsp;</li><li>Contribute to the development and execution of customer account plans for target accounts to deliver maximum impact opportunities and business goals&nbsp;</li><li>Deliver education to HCPs regarding product information, appropriate use, and dosing and administration based on FDA approved product information and formulary/pathways/guidelines (e.g. one on one interactions, in-services, identification of opportunities for peer-to-peer programming, etc.)</li><li>Effectively triage to USMA experts as appropriate</li><li>Address product acquisition (contract awareness, etc), and address supply matters through coordination of distribution issues, and managing spoilage and returns</li><li>Ensure product access to provide proactive (and de-identified) education on patient assistance, reimbursement resources. </li><li>Triage to HD and FRM as appropriate</li><li>Keep abreast of customer and healthcare industry trends. </li><li>Initiates development actions to constantly adapt and grow capabilities to increase impact</li><li>Represent the products to the highest ethical and professional standards and in accordance with guidelines and PRC approved materials</li><li>Lead, act and live our Operating Principles in all aspects of work</li></ul> Requirements: <ul><li>Scientific or clinical degree, Bachelor’s degree level at minimum</li><li>Previous cross-functional industry experience in commercial life sciences (pharma or biotechnology) or related industry engaging with key healthcare ecosystem players (e.g., payers, health systems), is required</li><li>4 or more years experience working in a sales role with HCPs, ideally representing multiple products and working across a complex healthcare system environment</li><li>You have sold specialty drugs before, have product launch experience and may have specific hemophilia, rare disease and/or orphan drug experience</li><li>Clinical nurse or Advanced Practice Nurse (APN) experience highly valued</li><li>Ability to work in an ambiguous environment undergoing transformation is a strong plus</li><li>Proven track record in coaching, training and/or mentoring peers or others as assigned; helping such others to better meet or exceed their goals, targets and other responsibilities</li><li>Proven track record for consistently meeting or exceeding financial and/or other quantitative targets, as well as qualitative goals</li><li>Self starter; ability to seek out relevant information, prioritize, and apply information to solve complex problems in the ecosystem&nbsp;</li><li>Ability to assimilate and communicate complex clinical and product information&nbsp;</li><li>Knowledge of and ability to successfully addressing operational issues in the delivery of healthcare products to patients, such as reimbursement and supply</li><li>Understanding of external laws, codes and company policies that apply to the healthcare industry</li></ul>

Responsibilities: <ul><li>Develop state of the art causal learning, deep learning, and predictive techniques to help the organization understand the performance of omnichannel campaigns and optimize spend.</li><li>Run regular A/B experiments and perform statistical analyses to measure the effects of these experiments.</li><li>Work with other data scientists, engineers, and product partners to develop new machine learning approaches, and measurement strategies.</li><li>Manage and guide data science and data engineering elements of AI/ML projects related to revenue prediction and optimization across commercial and marketing channels (TV, mail, email, web, social, mobile, digital, etc.).</li><li>Collaborate within cross-functional teams to develop efficient measurement use cases (such as revenue simulation (what-if scenarios)) and define goals and deliverables.</li><li>Leverage forecasting and simulation-based modeling approaches to provide optimization recommendations of marketing and business plans.</li><li>Conduct advanced analysis on various marketing efforts to gauge performance, impact, and effectiveness against the desired results.</li><li>Drive the development, deployment, and industrialization of enterprise-level Measurement algorithms to make business impact from structured and unstructured data for our brands and the different therapeutic areas.</li><li>Act as subject matter expert for applicable data science and other advanced analytical methodologies, programs, and projects in relation to business impact measurement: revenue optimization, marketing mix, forecasting, campaign and tactic testing, etc.</li></ul> Requirements: <ul><li>We are looking for a seasoned leader and data scientist with an extensive track record in designing, developing, and evaluating ML models which focus on optimization of marketing strategies and tactics, customer journey and perceptions within campaigns, and revenue impact.&nbsp;</li><li>As a Data Science Senior Manager - Measurement, you: Are energized to work collaboratively with partners and stakeholders across the business to apply, innovate, and deploy machine learning algorithms and data science methods for new measurement.</li><li>Will inform and empower Commercial and Medical stakeholders in marketing, finance, strategy teams, and the field to make data-driven decisions for patient benefit.</li><li>Drive to optimize investments and activities so that our client can create ever-improving, integrated customer experiences across brands and channels.</li><li>Deliver these benefits using robust and consistent methods that you have embedded in analytics products that can evolve and improve over time.</li></ul>

Responsibilities: <ul><li>Offering Second level of support for all application/reagents, provides specialized technical support/advice/information by interfacing directly with Customers and appropriate Commercial Support colleagues and functions. Interfaces with GSS and the Local Safety Officer in order to ensure rapid turnaround time of escalated complaints/inquiries.</li><li>Leveraging his/her unique expertise in laboratory medicine, provides guidance to first line of support staff on how to approach, resolve and communicate solutions to the customers, both in a verbal and written format. Also provides coaching to customers as part of a continuing education/skills enhancement program. Collaborate with Sales/Marketing in order to write documents (reports, articles, papers, memos, letters, etc…) that could be used to promote our products. Write documents for customers: the contents of these documents may include correlation results, study protocol, etc.</li><li>Develop and sustain strong relationships with Clinical Biochemists, Medical Biochemists, Pathologists, Laboratory leadership across Canada. Acts as an expert advisor for the customers and Global development and support teams on projects involving reagent applications. Reviews relevant technical update and other literature, undertakes research, attends advanced global application training sessions and product update sessions and maintains an effective knowledge network related to all clinical applications on the different instrument platforms.</li><li>Create and manage a “sentinel” network of Canadian laboratorians to provide an early warning for quality issues of our products</li><li>Assist and support Marketing in their attempts to define more value for our customer with our product offering. Reach out to colleagues of Commercial Support, but also Sales and Marketing in defining customer support solution that delivers value to our customers.</li><li>Establishes Key Performance Indicators for taking cases, entering data, managing customer, escalating complaints to Global, controlling costs, etc.</li><li>Acts as Roche’s trusted advisor with professional associations (e.g. CSCC, IQMH, etc) including maintaining an understanding of the different accreditation requirements and proficiency testing programs in all Canadian provinces. Maintains an open line of communication with these different organizations in order to ensure rapid response to our customer base in case of complaints/inquiries.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</li><li>Advise Regulatory and product life cycle groups regarding product design and use in Canadian market&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</li><li>Collaborate with the Regulatory and Quality teams to represent the interest of Canada commercial organization and its customers for scientific, technical, quality and safety issues</li><li>Responsible for scientific, technical, quality and safety narrative for customer communication</li><li>Coordinate and summarize scientific and technical information from relevant stakeholders for input in Canada product recall and other quality or complaint communications</li><li>Assist the Regulatory and Quality teams in communications with Health Canada&nbsp;</li></ul> Requirements: <ul><li>Ph D. in Biochemistry or Clinical Biochemistry and post-doctoral diploma in clinical biochemistry or clinical microbiology is a definitive plus</li><li>Certificate degree in management a plus</li><li>Canadian Board (FCACB) or American Board Certification (FACB) or Local Board OCQ specialist</li><li>Member of CSCC or any provincial laboratory medicine clinical society or equivalent</li><li>At least 3 years of experience in Clinical laboratory&nbsp;</li><li>Several years of hands-on experience with solving problems in the clinical laboratory</li><li>In this position, you will be servicing customers across Canada, therefore a proficient level of English is required and French is required.</li><li>Very good understanding of Laboratory Standards (International and Canadian)</li><li>Leadership skills, excellent communication skills and customer management experience all necessary for this job.</li><li>Experience interacting with Health Canada</li></ul>

Overview: <ul><li>As an EHS coordinator, you are part of an EHS team that is responsible for advising and supporting the planning, implementation, monitoring and optimization of business processes in the field of health and safety, the environment and safety.&nbsp;</li><li>You contribute to ensuring that everyone comes home from work safely every day and that complies with the relevant environmental, health and safety legislation, customer requirements</li><li>As an EHS coordinator you work from our office in Gorinchem but working from home is possible.&nbsp;</li><li>You are part of a multidisciplinary team with experienced and motivated safety experts.&nbsp;</li></ul> Responsibilities: <ul><li>You are the responsible EHS coordinator for part of the site.</li><li>You report to the Site Manager EHS</li><li>Developing the EHS policy in the relevant zone and leading and preparing various (management) meetings.</li><li>Provide solicited and unsolicited advice to continuously improve the environmental, health and safety performance of the site.</li><li>Assist in the management of the sites environmental, health and safety requirements, risk assessments, procedures and work instructions.</li><li>Follow up and investigate reported unsafe situations and observations.</li><li>Contribute and increase knowledge and awareness on the ground on a wide range of environmental, health and safety topics.</li><li>Promote a culture that raises behavioral awareness through coaching and by challenging unsafe practices and behaviors, both at the workplace and at management level.</li></ul>&nbsp;Requirements: <ul><li>EHS experience preferably in an industrial environment (ideally in a chemical or BRZO environment).</li><li>Environmental experience and/or diploma.</li><li>Experience in the field of safety and/or a diploma in Safety Science or the willingness to obtain this in the (short) term is an advantage.</li><li>You speak and write Dutch fluently and you understand English</li><li>You are driven to achieve results and finish what you started.</li><li>You take ownership of certain EHS topics and get energy from improving them.</li><li>You work independently and can set priorities.</li><li>You are able to communicate and motivate at various levels within the organization.</li><li>You can also work out with a personal trainer on our site at a reduced rate and participate in our social fund.</li></ul> Other Information: <ul><li>In addition to a good monthly salary, you also have a 13th month with us, an annual bonus, 25 days off and a good pension scheme with a very low employee contribution.&nbsp;</li><li>Culture that is characterized by empowering people and where your initiatives and ideas really make a difference</li><li>International focus with a great diversity of teams</li><li>Unique opportunity to be trained by our in-house experts in the world of bio-based products.</li><li>We invest in relevant training related to your specific discipline, giving you the opportunity to grow within your field</li><li>Finally, we offer a friendly, informal culture within a demanding and professional environment</li><li>In addition, we embrace diversity in our collaboration, which is part of our shared goals and values.&nbsp;</li><li>By committing to you become an employee in a company where you can be proud of your achievements.&nbsp;</li><li>We offer you the opportunity to further develop your career with global prospects.</li></ul>

Skills

Industry

Location

Jobtitle

5 biotechnology Jobs found

Scientist - Bioprocess Development

Therapeutic Area Account Manager, Hematology

Data Science Senior Manager, Measurement

The Laboratory Medicine Quality and Safety lead

Environment, Health & Safety Coordinator